DESCRIPTION
Product name Recombinant Human Galectin-3 Antigen
SPECIFICATIONS
Galectin-3 (Gal-3) is also known as LGALS3, It is the only chimera member of the Galectins family. It is formed by cross-linking a glycosyl with a non-glycosyl ligand. Gal-3 includes 3 binding domains, NH2 terminal binding domain, 1 sugar structure recognition domain and 1 A unique domain rich in glycine and proline repeats. LGALS3 / Galectin-3 is expressed in the nucleus, cytoplasm, mitochondrion, cell surface, and extracellular space. LGALS3 / Galectin-3 has been shown to be involved in the following biological processes: cell adhesion, cell activation and chemoattraction, cell growth and differentiation, cellcycle, and apoptosis.Galectin 3 is involved in regulating cell growth, anti-apoptosis, mediating cell adhesion, and participating in biological functions such as blood vessel formation and inflammation. Studies have shown that Galectin-3 is a marker of myocardial fibrosis and is associated with the occurrence of heart failure and an increased risk of death. The content of galectin-3 in patients with ventricular dysfunction will increase, and the content is directly related to the severity of heart failure.
相似产品
Galectin-3 Ab
Catalog#:RXS001Ab04-1000
Reactivity:human
Source:Mouse, IgG1 Kappa
Application:ELISA, others unspecified
了解更多