Recombinant Human Galectin-3 Antigen

产品编号:RXS001Ag*C-1000

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DESCRIPTION 

  • Product name                              Recombinant Human Galectin-3 Antigen

  • Cat No                                            RXS001Ag*C-1000
  • Lot                                                  20220824
  • Source                                            E. coli­derived
  • Accession #                                   P17931
  • N-terminal Sequence Analysis     Ala2
  • Predicted Molecular Mass            26 kDa
  • Corcentration                                1.8mg/ml


SPECIFICATIONS

  • SDS PAGE                                      26 kDa, reducing conditions.
  • Activity                                           Measured by its ability to agglutinate human red blood cells. Hadari, Y.R. et al.(2000) J. Cell Sci. 113:2385.The ED50 for this effect is 3 10 µg/mL.
  • Endotoxin Level                             <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity                                               >96%,by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Formulation                                    Supplied as a 0.2 μm filtered solution in PBS, pH 7.4,5%Glycerol.


  • Galectin-3 (Gal-3) is also known as LGALS3, It is the only chimera member of the Galectins family. It is formed by cross-linking a glycosyl with a non-glycosyl ligand. Gal-3 includes 3 binding domains, NH2 terminal binding domain, 1 sugar structure recognition domain and 1 A unique domain rich in glycine and proline repeats. LGALS3 / Galectin-3 is expressed in the nucleus, cytoplasm, mitochondrion, cell surface, and extracellular space. LGALS3 / Galectin-3 has been shown to be involved in the following biological processes: cell adhesion, cell activation and chemoattraction, cell growth and differentiation, cellcycle, and apoptosis.Galectin 3 is involved in regulating cell growth, anti-apoptosis, mediating cell adhesion, and participating in biological functions such as blood vessel formation and inflammation. Studies have shown that Galectin-3 is a marker of myocardial fibrosis and is associated with the occurrence of heart failure and an increased risk of death. The content of galectin-3 in patients with ventricular dysfunction will increase, and the content is directly related to the severity of heart failure.

Recombinant Human Galectin-3 Antigen(RXS001AgC-1000)_说明书

  •  Cat.                                   Clone number        Description
  • RXS001Ab04-1000            6-4G11                 Monoclonal antibody raised against recombinant human Galectin-3.
  • RXS001Ab05-1000            E8H3                 Monoclonal antibody raised against recombinant human Galectin-3.
  • RXS001Ab06-1000            E15F10         Monoclonal antibody raised against recombinant human Galectin-3.
  • RXS001Ab07-1000            Q1E2                 Monoclonal antibody raised against recombinant human Galectin-3.
  • RXS001Ab013-1000    X4B4                 Monoclonal antibody raised against recombinant human Galectin-3.
  • RXS001Ab014-1000    Y7E12                 Monoclonal antibody raised against recombinant human Galectin-3.

  

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